基本信息
小麦产量遗传学，作物调控组学
2002.09-2006.06 yl6809永利，生物科学，学士
2006.09-2012.12 yl6809永利，遗传学，博士
2013.03-2017.05 德国波茨坦大学, 博士后
2017.06-2019.03 德国洪堡大学, 博士后
2019.03 至今 yl6809永利, 教 授
本人过去十多年主要围绕植物花期的遗传基础和花（序）的发育调控开展研究。在研究中结合经典遗传学、分子生物学、调控组学等手段，先后克隆了2个控制水稻开花期及穗大小的主效基因；并从基因的转录调控、染色质修饰和活性等多个层面研究了植物花发育过程中的调控机制。相关研究结果发表在Molecular Plant、Cell Research、New Phytologist、Nature Plants及Nature Communications等杂志上。2019年3月入职yl6809永利yl6809永利，从事小麦产量性状形成的遗传及分子调控基础的研究。本课题组将充分利用在模式植物拟南芥和水稻中积累的经验、知识以及相关技术体系，围绕着小麦开花期及穗发育的调控网络以及小麦多倍化的调控生物学基础等问题开展研究工作。
研究论文：(#,共同第一作者；*，通讯作者)
1. Wenhao Yan#, Dijun Chen#, Julia Schumacher, Diego Durantini, Julia Engelhorn, Ming Chen, Christel Carles, and Kerstin Kaufmann. Dynamic control of enhancer activity drives stage-specific gene expression during flower morphogenesis. Nature Communications, accepted.
2. Dijun Chen#, Wenhao Yan#, Liang-Yu Fu and Kerstin Kaufmann*. Architecture of gene regulatory networks controlling flower development in Arabidopsis thaliana. Nature Communications, 2018, 9:4534.
3. Wenhao Yan#*, Dijun Chen#, Cezary Smaczniak, Engelhorn Julia, Haiyang Liu, Wenjing Yang, Alexander Graf, Christel Carles, Dao-Xiu Zhou, and Kerstin Kaufmann*. Dynamic and spatial restriction of polycomb activity by plant histone demethylases. Nature Plants, 2018, 4: 681–689.
4. Julia Schumacher, Kerstin Kaufmann, and Wenhao Yan*. Multiplexed guideRNA-expression to efficiently mutagenize multiple loci in Arabidopsis by CRISPR-Cas9. Bio-protocol, 2017, e2166.
5. Wenhao Yan*, Dijun Chen and Kerstin Kaufmann*. Efficient multiplex mutagenesis by RNA-guided Cas9 and its use in the characterization of regulatory elements in the AGAMOUS gene. Plant Methods, 2016, 12: 23
6. Wenhao Yan, Dijun Chen and Kerstin Kaufmann*. Molecular mechanisms of floral organ specification by MADS domain proteins. Current Opinion in Plant Biology, 2016, 29:154–162
7. Jia Zhang#, Xiangchun Zhou#, Wenhao Yan#, Zhanyi Zhang, Li Lu, Zhongmin Han, Hu Zhao, Haiyang Liu, Pan Song, Yong Hu, Guojing Shen, Qin He, Sibin Guo, Guoqing Gao, Gongwei Wang and Yongzhong Xing*. Combinations of the Ghd7, Ghd8 and Hd1 genes largely define the ecogeographical adaptation and yield potential of cultivated rice. New Phytologist, 2015, 208: 1056-1066
8. Wenhao Yan#, Haiyang Liu#, Xiangchun Zhou, Qiuping Li, Jia Zhang, Li Lu, Touming Liu, Haijun Liu, Chengjun Zhang, Zhanyi Zhang, Guojing Shen, Wen Yao, Huaxia Chen, Sibin Yu, Weibo Xie, Yongzhong Xing*. Natural variation in Ghd7.1 plays an important role in grain yield and adaptation in rice. Cell Research, 2013, 23: 969-971.
9. Li Lu#, Wenhao Yan#, Weiya Xue, Di Shao, Yongzhong Xing*. Evolution and association analysis of Ghd7 in rice. Plos one, 2011, 7:e34021.
10. Wenhao Yan#, Peng Wang#, Huaxia Chen, Hongju Zhou, Qiuping Li, Chongrong Wang, Zehong Ding,Yushan Zhang, Sibin Yu*, Yongzhong Xing* and Qifa Zhang. A major QTL, Ghd8, plays pleiotropic roles in regulating grain productivity, plant height, and heading date in rice. Molecular Plant, 2011, 4: 319-330.
参编书籍：
Wenhao Yan, Zhongmin Han, and Yongzhong Xing*. Molecular diagnostics in rice (Oryza sativa). Chapter 20 of Diagnostics in Plant Breeding, 2013, pp 443-465
